Case story database

Search for Successfully Implemented Alternatives

You can use the free text search function to find information in the case story database. Most suitable are: substance name and other substance identifier (EC- and CAS-number). You can refine your search after first entry for sector-, function- and process-categories. The case studies are meant to serve as source of inspiration and ideas for substitution. The alternatives are constantly being developed further. We therefore recommend that you to check in each individual case whether an alternative is suitable for your applications and purposes. If you are aware of any other relevant information that is not mentioned in the current case story, please contact SUBSPORTplus.

In order to utilize information in the best way, please take note of the SUBSPORTplus methodology on case stories!

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Alternative to formaldehyde as preservative in water samples

A well-known preservative, formaldehyde, is also a carcinogen and a sensitiser. Its use for preserving macroinvertebrates in fresh water samples can be substituted by freezing parts of the samples and using ethanol for the other parts.

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70% ethanol as an alternative to formalin in tissue fixation

70% ethanol fixation and paraffin embedding is a useful alternative method for molecular profiling studies. This was shown during a systematic approach of processing clinical tissue specimen (prostate and kidney) through non-formalin fixation method.

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