Case story database

Search for Successfully Implemented Alternatives

You can use the free text search function to find information in the case story database. Most suitable are: substance name and other substance identifier (EC- and CAS-number). You can refine your search after first entry for sector-, function- and process-categories. The case studies are meant to serve as source of inspiration and ideas for substitution. The alternatives are constantly being developed further. We therefore recommend that you to check in each individual case whether an alternative is suitable for your applications and purposes. If you are aware of any other relevant information that is not mentioned in the current case story, please contact SUBSPORTplus.

In order to utilize information in the best way, please take note of the SUBSPORTplus methodology on case stories!

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Healthy business strategies for transforming the Toxic Chemical Economy

The report synthesises and presents a coherent approach any firm can adopt to move towards a fully integrated healthy business strategy. It provides six examples of companies that are adopting healthy strategies.

Screening study to identify reductions in VOC emissions due to restrictions to the VOC content of products

Study done by the European Commission in order to reduce or eliminate the use of VOC in different products. It proposes several alternatives.

Solvent substitution in industry: development of an intervention strategy

The document offers a critical review of literature on solvent substitution and its requirements. It provides alternatives for the use of solvents.

Organic solvents. Monograph.

The document describes health and environment problems caused by the use of solvents in the workplace. Alternatives like esters or wet cleaning are proposed to replace many of the applications of organic solvents.

Evaluation of solvent substitutes

This document presents a process that can be used to evaluate parts cleaning alternatives to solvents.

Substitution von Methanol durch Ethanol bei der Fixierung von Polyacrylamidgelen für die Analyse von Proteinen und DNA/RNA .

Methanol wird in einem Fixierungsprozess verwendet, der bei der Analyse
von Proteinen und DNA/RNA in Polyacrylamidgelen erforderlich ist. Diese Fixierung ist
notwendig, um Proteine oder Nukleinsäuren in große unlösbare Aggregate
umzuwandeln, die nicht reagieren oder zerfallen können. Ethanol ist ein
gutes Substitut für Methanol, da es weniger toxisch und die Arbeit mit
dem Stoff somit sicherer ist.

Die Substitution funktioniert bei der
Western Blot Analyse und der Aufbereitung von Membranen nicht gut. Es
sollte daher nicht für PVDF-Membranen verwendet werden.

A review of different fire retardant technologies from a safe environmental hazard and risk performance.

A review of alternate flame retardant technologies including information about flame retardant currently in use, alternatives to these available on the market as well as future solutions that might become available in a few years. Information is divided into product categories ranging from textiles to furniture and electronics. The basis of this case study is a report prepared for the Department of Environment, Foods and Rural Affairs (UK).

Substitution of methanol with ethanol for use in fixation of polyacrylamide gels in analysis of proteins and DNA/RNA.

Methanol is used in a fixation process required for analysis of proteins and DNA/RNA on polyacrylamide gels. Fixation is necessary for transforming the proteins or nucleic acids into large, insoluble aggregates which are unable to react or degrade. Ethanol is a good substitute for methanol since it´s less toxic and therefore safer to work with.

The substitution does not work well with Western blot analysis's and processing of membranes. It should also not be used on PVDF-membranes.

Substitution of PFC in paper with natural greaseproof paper.

This example concerns an alternative way to obtain grease-proof properties in papers used for cooking, baking or packaging food. Today, paper used for packaging of foodstuffs that require some grease resistance is made using chemicals such as perfluorinated compounds, these compounds are however associated with both human and environmental hazards. The technique described here provides a grease-proof surface by mechanically refining the cellulose fibers without the use of harmful chemicals.

Substitution von perfluorierten Verbindungen (PFC) in Papier durch natürliches fettdichtes Papier

Dieses Beispiel betrifft eine alternative Möglichkeit, fettdichte Eigenschaften von Papieren, die beim Kochen, Backen oder der Verpackung von Lebensmitteln verwendet werden, zu erwirken. Heutzutage wird zur Verpackung von Lebensmitteln Papier mit fettabweisender Wirkung eingesetzt, das unter der Verwendung von Chemikalien wie perfluorierten Verbindungen hergestellt wird. Diese Verbindungen werden allerdings sowohl mit Gefahren für den Menschen als auch für die Umwelt in Verbindung gebracht werden. Die hier beschriebene Technik bietet eine fettdichte Oberfläche durch die mechanische Veredelung der Zellulosefasern ohne die Verwendung von schädlichen Chemikalien.

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