Reactive substances consisting of Fluorine, Chlorine, Bromine, Iodine or Astatine.
Intrinsic property of a substance which is always present. See also Risk.
High Production Volume chemical, manufactured/imported at more than 1000 tonnes/year.
Testing within a living organism.
Indicative Occupational Exposuer Limit Value
Octanol-Water Partition Coefficient is a coefficient representing the ratio of the solubility of a compound in octanol to its solubility in water. The higher the KOW, the more soluble is the compound in non-polar, organic solvents. Log KOW is generally used as a relative indicator of the tendency of an organic compound to adsorb to soil. Log KOW values are generally inversely related to aqueous solubility and directly proportional to molecular weight.
The Lowest Observed Adverse Effect Concentration is the lowest tested concentration at which there are statistically significant increases in frequency or severity of adverse effects between the exposed population and an appropriate control group.
The Lowest Observed Adverse Effect Level is the lowest tested dose or exposure level at which there are statistically significant increases in frequency or severity of adverse effects between the exposed population and an appropriate control group.
The Lowest Observed Effect Level is the lowest tested dose or exposure level at which, in a study, a statistically significant effect is observed in the exposed population compared with an appropriate control group.
Low Production Volume chemical, manufactured/imported at more than 100 tonnes/year.
Any national or legal person established within the Community who manufactures a substance within the Community
Production or extraction of substances in the natural state
A solution composed of two or more substances.
Member State Competent Authority. The authority in each EU Member state which monitors REACH and other chemical issues.
Causes irreparable mutations in the DNA which will be transferred on to the next generation.