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Search for Successfully Implemented Alternatives

You can use the free text search function to find information in the case story database. Most suitable are: substance name and other substance identifier (EC- and CAS-number). You can refine your search after first entry for sector-, function- and process-categories. The case studies are meant to serve as source of inspiration and ideas for substitution. The alternatives are constantly being developed further. We therefore recommend that you to check in each individual case whether an alternative is suitable for your applications and purposes. If you are aware of any other relevant information that is not mentioned in the current case story, please contact SUBSPORTplus.

In order to utilize information in the best way, please take note of the SUBSPORTplus methodology on case stories!

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Alternatives to 2-methoxyethanol as put forward by the European Chemicals Agency (ECHA)

This document concerns the general toxicity of 2-methoxyethanol and some common alternatives to its use in different applications. The most common substitutes for 2-methoxyethanol are: PGME, EGBE, ethylene glycol monopropyl ether (EGPE) and their acetates (PGMEA, EGBEA, EGPEA). The decision which alternative to use depends on what application 2-methoxyethanol is currently used in.

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Substitution of concentrated sodium hydroxide with sodium hydrogen carbonate for pH adjustment in pharmaceutical production.

Neutralisation of a product during a pharmaceutical production was earlier done by applying sodium hydroxide. Sodium hydroxide was substituted with the less hazardous alternative sodium hydrogen carbonate.

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Reduction of chlorine for disinfection in swimming pools

Chlorine is used as a disinfectant in swimming pools. Chlorine has the advantage of being effective against a considerable number of microorganisms. When adding free chlorine to swimming pool water, however, a very large number of unwanted chlorinated by-products are formed. Other compounds can be used for disinfection, but they are not as efficient and fast-acting as chlorine. But if e.g. silver compounds are combined with a non-chemical alternative as filtration a good result can be achieved.

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