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A bill (see definitinon) that has become law, in USA legislation


An object which during production is given a special shape, surface or design, which determines its function to a greater degree than does its chemical composition. Examples of articles are a car, a battery and a telephone, according to REACH (see definition).


BCF = Bioconcentration factor-parameter (L/kg) that gives an indication of the accumulation potential of a substance in an organism.Can either be expressed as the ratio of the concentration of a substance to the concentration in water once a steady state has been achieved (static BCF), or, on a non-equillibrium basis, as the quotient of the uptake and depuration rate constants (dynamic BCF).

Benchmark dose

The dose causing a predetermined change in response.The BMD concept involves fitting a mathematical model to dose-response data.


Document under consideration prior to becoming an act (see definition) in the USA legislation system.


A property causing the substances to build up (accumulate) in the body. Such substances build up in fat tissue in the body and can not be excreted by the body.


Binding Occupational Limit Value (Bindender Arbeitsplatzgrenzwert)


Chemical Agents Directive 98/24/EG

Candidate list

A list of substances within REACH meeting the criteria of Substances of Very High Concern, and proposed by either the European Commission or the EU Member states. These substances are candidates for REACH Authorisation.


A carcinogenic substance causes cancer.

CAS number

Chemical Abstracts Services registration number. A unique number assigned to each substances submitted to CAS. Used world wide to positively identify chemicals.


A chemical is another word for substance or compound. Identified by a unique CAS or EC-number.

Siehe auch


Regulation on classification, labelling and packaging of substances and mixtures (CLP-Regulation, Regulation (EC) No. 1272/2008).


Cancerogen and Mutagen Directive 2004/37/EG


The abbreviation for Carcinogenic, Mutagenic and toxic to Reproduction, chemicals with inherent properties which can cause cancer, alter DNA and damage reproductive systems. Part of the REACH Substances of Very High Concern.


Process of bringing together a EU legislative act and all its amendments in a single new act. The new act passes through the full legislative process and replaces the acts being codified.


if not specified otherwise) = European Commission is the executive body of the European Union responsible for proposing legislation, implementing decisions, upholding the Union’s treaties and the general running of the Union.The Commission is divided into departments known as Directorates-General (DGs) e.g. DG Environment.


Combining in a single EU legislative text the provisions of a basic instrument and all subsequent amendments. Consolidated texts are used for practical reasons only, they have no legal value.


Legislative act of the European Union, which requires Member States to achieve a particular result without dictating the means of achieving that result.


The Derived Minimal Effect Level. For non-threshold effects, the underlying assumption is that a no-effect-level cannot be established and a DMEL expresses an exposure level corresponding to a low, possibly theoretical, risk, which should be seen as a tolerable risk.


The Derived No-Effect Level is the level of exposure to the substance below which no adverse effects are expected to occur. It is the level above which humans should not be exposed. DNEL is a derived level of exposure because it is normally calculated on the basis of available dose descriptors from animal studies such as No Observed Adverse Effect Levels (NOAELs) or benchmark doses (BMD).

Downstream user

A user of a chemical produced by a manufacturer. This can be a formulator, article manufacturer or a consumer.

EC number

European Commission registration number. The unique number under which a substance is registered in the European Union.


The European Chemicals Agency in Helsinki, Finland, established to oversee and implement the REACH Regulation and the Biocidal Products Regulation.


Endocrine Disruptor Chemical. A substance that disrupts or alters the hormonal systems in the body, causing widespread effects throughout the organism. These effects can be observed at extremely low doses.


Electrical and electronical equipment: the functionality of the equipment depends on electrical current or electromagnetic fields or the equipment is used to generate, transfer and measure electrical current or electromagnetic fields.


European Inventory of Existing Commercial Chemical Substances, which lists reported substances on the EU market before 18th September 1981.


European List of Notified Chemical Substances. ELINCS is comprehensive of all notified substances, concluded by expiry of the Directive 67/548/EEC on 31st May 2008. On 1st June 2008 the notification scheme was replaced by Regulation (EC) No 1907/2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH).

Endocrine disruptor (ED)

A substance that disrupts or alters the hormonal systems in the body causing widespread effects throughout the organism. These effects can be observed at extremely low doses.

Equivalent level of concern

The safety net of the REACH regulation for substances which do not automatically fall into the categories CMR, PBT or vPvB but is of equivivalent level of concern in terms of the potential damage it may cause.


European chemical Substances Information System, available until end of 2012. A former IT System with information on chemicals related to Biocidal Products, on PBT or vPvB substances, on Classification and Labelling etc. Since 2008, most information is available in the database of the European Chemicals Agency (ECHA).

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