Case story database

Search for Successfully Implemented Alternatives

You can use the free text search function to find information in the case story database. Most suitable are: substance name and other substance identifier (EC- and CAS-number). You can refine your search after first entry for sector-, function- and process-categories. The case studies are meant to serve as source of inspiration and ideas for substitution. The alternatives are constantly being developed further. We therefore recommend that you to check in each individual case whether an alternative is suitable for your applications and purposes. If you are aware of any other relevant information that is not mentioned in the current case story, please contact SUBSPORTplus.

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Substitution von Formaldehyd als Gewebefixiermittel

Formaldehyd ist eine organische Verbindung, die als Gewebefixiermittel in der Mikroskopie und Histologie verwendet wird. Das Formaldehyd wurde durch ein Produkt mit dem gewerblichen Namen Fixall-his substituiert, das Ethanol, Isopropanol und Essigsäure enthält.

Substitution of formaldehyde as a tissue fixative

Formaldehyde is an organic compound used as a tissue fixative for microscopy and histology. Formaldehyde was substituted by a product containing: ethyl alcohol, isopropyl alcohol and acetic acid under the commercial name Fixall-his.

Alternative to formaldehyde in fluid preservation of biological specimens.

22 alternatives were assessed as alternatives to formaldehyde in preserving biological specimens. DMDM-hydantoin was regarded as a suitable alternative. DMDM-hydantoin is also used in pharmaceutical and cosmetic products.

70% ethanol as an alternative to formalin in tissue fixation

70% ethanol fixation and paraffin embedding is a useful alternative method for molecular profiling studies. This was shown during a systematic approach of processing clinical tissue specimen (prostate and kidney) through non-formalin fixation method.

Insulating and waterproof alternatives

The sector of bio-construction uses insulating and watertight materials as an alternative to conventional man-made materials like polystyrene, polyurethane and other chemicals harmful for the environment. This article introduces 19 different types of insulating and watertight materials with a description of their properties, applications and technical characteristics. The alternative materials include: sheets of polypropylene, recycled paper cellulose fibre, hemp blankets, thermo-fixed flax paper, wood fibre panels, sheep wool blankets, coconut fibre, feather panels, cotton blankets, straw balls, straw and lime, cellular glass, pearlite, expanded clay, vermiculite and hops.

Alternative to formaldehyde as preservative in water samples

A well-known preservative, formaldehyde, is also a carcinogen and a sensitiser. Its use for preserving macroinvertebrates in fresh water samples can be substituted by freezing parts of the samples and using ethanol for the other parts.

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